Prolonged remission in Di Guglielmo's syndrome.

Di Guglielmo's syndrome with low serum vitamin B12.

The natural history of trilinear myelodysplastic syndrome and erythroleukemia.

A case of Di Guglielmo's syndrome passed through the three stages of chronic erythromyelosis, erythroleukemia and acute myeloid leukemia (AML). According to the FAB classification the subsequent stages of this syndrome were refractory anemia (RA), RA with excess of blasts (RAEB), AML-M6, AML-M2 and undifferentiated AML-MO as the end-stage disease. Light- and electronmicroscopice findings on per...

Autonomous erythropoiesis during erythroblastic crisis of chronic myelocytic leukemia.

Two patients with chronic myelocytic leukemia who developed an erythroblastic rather than a myeloblastic phase were studied with respect to whether or not the megaloblastic erythropoiesis was subject to normal control mechanisms. After transfusion, no significant reduction was observed in the percentage of nucleated erythroid precursors or of proerythroblasts in marrow or in blood reticulocytes...

Experimental research on the proliferative and differentiative activity of the erythroblast in chronic erythremia, the chronic form of Di Guglielmo's disease.

LOW DOSE PREDNISOLONE WITH INCREASE IN DOSAGE INTERVAL IN FREQUENT RELAPSING NEPHROTIC SYNDROME

In order to avoid using cytotoxic drugs and to minimize prednisolone side effects in frequent relapsing or steroid-dependent idiopathic nephrotic syndrome, 35 patients, 3 to 15 (mean= 8.1) years of age, were studied. While in remission for at least 6 weeks, the dose of prednisolone was reduced to 0.1-0.37 (mean= 0.23) mg/kg/day as a single dose for 12 to 72 (mean= 27.6) months. It was follo...